Did you take Zofran while pregnant and have birth defect complications?

Zofran (ondansetron)5-HT3 receptor antagonists

Zofran is medication to treat nausea and is generally prescribed to patients who have undergone cancer treatments such as chemotherapy, radiation therapy and surgery. As Zofran became popular Doctors began to prescribe it to pregnant women in order to treat morning sickness. Glaxo the manufacturer of Zofran had prior knowledge of a potential increase in birth defects, but continued to market the drug. Women are now bringing lawsuits against Glaxo because of these side effects.

What is Zofran?

Zofran (Ondansetron) belongs to a class of medications called 5-HT3 receptor antagonists and works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

Zofran is prescribed to patients with nausea and vomiting who have undergone cancer chemotherapy, radiation therapy and surgery. It is not prescribed to not for preventing nausea or vomiting that is caused by factors other than cancer treatment or surgery.

Manufactured and sold by GlaxoSmithKline, it was the first in its class, and the FDA approved its use in 1991. While the Zofran is only approved for use in treating nausea and vomiting after chemotherapy, radiotherapy or after surgery, doctors will sometimes use it for off-label uses such as treating stomach problems in children and morning sickness in expectant mothers.

Adverse Reactions to Zofran

In 2014, a Zofran study was published in the American Journal of Obstetrics and Gynecology. The results presented showed that use of Zofran while pregnant almost doubled the increase of birth defects. . It was also shown that the drug could cross the placental barrier and be excreted in breast milk. Zofran is currently facing a number of lawsuits in relationship to this finding.

In addition to the increased risk of birth defects in pregnant woman, Zofran has a number of other potential side effects that you should watch for including:

Serious Side Effects:

  • Blurry vision
  • Shortness of breath
  • Confusion
  • Excessive sweating
  • Seizures
  • Coma
  • Loss of consciousness
  • Chest pain
  • Hives or rash
  • Swelling

Common Side Effects:

  • Headache
  • Constipation
  • Weakness
  • Tiredness
  • Chills
  • Drowsiness
  • Diarrhea

Most frequent Zofran reactions

The U.S. Food and Drug Administration (FDA) regulates over-the-counter and prescription drugs in the United States, including biological therapeutics and generic drugs. This work covers more than just medicines. For example, fluoride toothpaste, antiperspirants, dandruff shampoos and sunscreens are all considered drugs.

An adverse event is submitted to the FDA to report any undesirable experience associated with the use of a medical product in a patient. For drugs, this includes serious drug side effects, product use errors, product quality problems, and therapeutic failures for prescription or over-the-counter medicines and medicines administered to hospital patients or at outpatient infusion centers.

Regarding more information related to this product please check out this link to the FDA website.

Call now to discuss your legal options.

Current Zofran Lawsuits

Currently law firms are accepting claims against Glaxo. The claims are being made to hold Glaxo liable for injuries suffered by babies whose mothers took the medication while pregnant. Court documents show that Glaxo knew as early as 1992 that Zofran presented “unreasonable risk of harm” to fetal development and continued to market the drug to pregnant women.

If you or a loved one has suffered from birth defects from taking Zofran, you may be eligible to file a lawsuit or join a Zofran class action lawsuit.

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