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SGLT2 Inhibitorstype 2 diabetes treatment

SGLT2, or Sodium-Glucose CO-Transporter 2 Inhibitors, are a class of drugs used to treat Type II Diabetes. SGLT2 Inhibitors control blood sugar levels by stopping the glucose from being reabsorbed into the blood. Researchers ahve found that in some cases, the use of SGLT2 Inhibitors may cause diabetic ketoacidosis [explain]. Currently, attorneys are actively looking for users who ahve suffered from diabetic ketoacidosis because of the use of SGLT2 Inhibitors.

What are SGLT2 Inhibitors?

SGLT2 (Sodium-Glucose Co-Transporter 2) Inhibitors are a newer cateogry of Type II Diabetic drugs. The first drug in this class, Invokana by Johnson & Johnson, was approved for use by the FDA in March 2013. A number of other drugs followed soon after. Basically, SGLT2 Inhibitors help to control blood sugar levels by stopping the glucose from being reabsorbed by the blood.

When a normal person consumes good, their body produces insulin to process the sugars in the food. People with Type II Diabetes no longer work this way and develop a resistance to insulin. Eventually, their pancreas cannot keep up with the demand for insulin which causes their blood sugar levels to rise. The SGLT2 Inhibitors prevents this by stopping the sugar from being reabsorbed into the blood.

SLGT2 Inhibitor Drugs Include:

  • Farxiga (dapagliflozin)
  • Invokana (canagliflozin)
  • Invokamet (canagliflozin and metformin)
  • Jardiance (empagliflozin)
  • Glyxambi (empagliflozin and linagliptin)
  • Xigduo XR (dapagliflozin and metformin extended-release)

Adverse Reactions to
SGLT2 Inhibitors

In May 2015, the FDA issued a warning that SGLT2 Inhibitors may lead to diabetic ketoacidosis (DKA) which can be fatal. DKA is considered a medical emergency and users should pay close attention to possible symptoms. Despite the concerns, the FDA does not recommend stopping use of the medication without first consulting your primary care physician.

 

Symptoms of Diabetic Ketoacidosis Include:

  • Confusion
  • Difficulty breathing
  • Unusual fatigue or sleepiness
  • Frequent urination or thirst that lasts for a day or more
  • Flushed face
  • Fruity-smelling breath
  • Aching muscles or muscle stiffness
  • Vomiting and nausea
  • Stomach pain

Additional Side Effects Include:

  • Low blood pressure
  • Increased LDL cholesterol
  • Yeast infection
  • High blood potassium levels

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Current SGLT2 Inhibitor Lawsuits

Attorneys are actively accepting cases involving SGLT2 Inhibitors if the user has developed diabetic ketoacidosis.

Current drugs included in possible lawsuits are:

  • Canagliflozin, marketed as Invokana, manufactured by Johnson & Johnson’s Janssen Pharmaceuticals
  • Canagliflozin and Metformin, marketed as Invokamet, also manufactured by J&J’s Janssen Pharmaceuticals
  • Dapagliflozin, marketed as Farxiga, manufactured by AstraZeneca
  • Dapagliflozin and Metformin extended-release, marketed as Xigduo XR, also manufactured by AstraZeneca
  • Empagliflozin, marketed as Jardiance, manufactured by Lilly and Boehringer-Ingelheim
  • Empagliflozin and Linagliptin, marketed as Glyxambi, manufactured by Lilly and Boehringer-Ingelheim

It is important for anyone who has dealt with this issue to seek legal representation immediately. Our lawyers will present your case along with those of the many others who have suffered disability and death as a result of SGLT2 inhibitor use, and seek the financial compensation you deserve.

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